Pathology

The most pronounced changes related to malaria involve the blood and the blood-forming system, the spleen and the liver. Secondary changes can occur in all the other major organs, depending on the type and severity of the infection. The pathological changes are more profound and severe in case of P.…

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Life Cycle

The malaria parasite has a complex, multistage life cycle occurring within two living beings, the vector mosquitoes and the vertebrate hosts. The survival and development of the parasite within the invertebrate and vertebrate hosts, in intracellular and extracellular environments, is made possible by a toolkit of more than 5,000 genes…

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Epidemiological Definitions

These definitions and indices are important in epidemiological surveillance and in planning the control strategy for malaria. Endemic Malaria: Constant incidence over a period of many successive years in an area. Epidemic Malaria: Periodic or occasional sharp increase of malaria in a given indigenous community. Stable Malaria: Amount of transmission…

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