(All states other than Jammu and Kashmir,
Himachal Pradesh and Sikkim and the North Eastern States
of Assam, Manipur, Nagaland, Mizoram, Tripura and Arunachal Pradesh)
National Vector Borne Disease Control Programme (NVBDCP) recommends
chemoprophylaxis for selective groups in high P. falciparum
endemic areas. Use of personal protection measures including Insecticide
Treated bed Nets (ITN) / Long Lasting Insecticidal Nets (LLIN) [See
Personal protection measures] is
encouraged for pregnant women and other vulnerable population including travellers for longer stay. However, for longer stay of Military and Para-military forces in high P. falciparum endemic areas, the
practice of chemoprophylaxis should be followed wherever appropriate,
e.g. troops on night patrol duty, and decisions of their Medical
Administrative Authority should be followed.
Short Term Prophylaxis (less than 6 weeks): Doxycycline, 100
mg daily in adults and 1.5 mg/kg for children more than 8 years old; it should be started 2 days before
travel and continued for 4 weeks after leaving the malarious area. Doxycycline is contraindicated in pregnant women and
children less than 8 years.
For long-term chemoprophylaxis (more than 6 weeks):
Mefloquine 5 mg/kg bw (up to 250 mg) weekly; it should be
administered two weeks before, during and four weeks after leaving the
area. Mefloquine is contraindicated in cases with history of
convulsions, neuropsychiatric problems and cardiac conditions.
of malaria | Chemoprophylaxis