Malarial anemia among pregnant women in the south-westerncoastal city of Mangaluru in India. Chandrashekar VN, Punnath K, Dayanand KK, Achur RN, Kakkilaya SB,Jayadev P, Kumari SN, Gowda DC. Informatics in Medicine Unlocked Feb 2019. doi: https://doi.org/10.1016/j.imu.2019.02.003. Malaria Severity in Mangaluru City in the Southwestern Coastal Region of India. Kiran K.…
Prophylaxis for the states of Jammu and Kashmir, Himachal Pradesh and Sikkim Malaria transmission is nil or very low in these states at a higher altitude. Routine chemoprophylaxis is therefore not essential for travelers to these states of the Indian Union. However it may be prudent to inquire about the…
Every year, more than 125 million people visit over 100 countries endemic for malaria. Each year up to 30 000 travelers are estimated to contract malaria and late or wrong malaria diagnosis in their home country may make things worse for them. Fever occurring in a traveler within three months…
Emergence of resistance to antimalarial drugs has become a major hurdle in the successful treatment of the infection, and has contributed significantly to global malaria-related mortality.[1] Till date, drug resistance has been documented in P. falciparum, P. vivax, and P. malariae.[1] P. falciparum has developed resistance to nearly all antimalarial…
Ideally, every case of malaria should be followed up to ensure the completion of treatment and parasitological cure. Any evidence of treatment failure, despite full treatment, and no vomiting, is an indication to treat with second line drugs without further delay. WHO has developed a revised protocol for assessment and…
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Go to Treatment of P. vivax / P. ovale / P. malariae | Treatment of Uncomplicated P. falciparum | Treatment of Severe Malaria Aims of Treatment Aims Causation Therapy Drugs To alleviate symptoms Symptoms are caused by blood forms of the parasite Blood schizonticidal drugs Chloroquine, quinine, artemisinin combinations To…
Early and effective chemotherapy for malaria has a pivotal role in reducing morbidity and mortality especially since a vaccine is unlikely to emerge within the next decade. Multidrug resistance has been reported from most parts of the world and as a result, monotherapy or some of the available combination chemotherapies…
Primaquine is the essential co-drug with chloroquine in treating all cases of malaria. It is highly effective against the gametocytes of all plasmodia and thereby prevents spread of the disease to the mosquito from the patient. It is also effective against the dormant tissue forms of P. vivax and P.…
Mother Nature gave us the cinchona alkaloids and qinghaosu. World War II led to the introduction of chloroquine, chloroguanide (proguanil), and eventually amodiaquine and pyrimethamine. The war in Vietnam brought mefloquine and halofantrine. These drugs are all we have available now to treat malaria. It is difficult to see where…
